8.A.27.1.8
CDC50 family protein, Chat-1 of 348 aas and 2 TMSs, N- and C-terminal. It is a chaperone protein for the
phospholipid-transporting ATPase tat-1 (TC# 3.A.3.8.15) that regulates cell membrane
structure and function. It plays a role in maintaining the membrane
phosphatidylserine asymmetry and the formation of the tubular membrane
structure. It is involved in membrane trafficking and is specifically involved
in the recycling and degradation of endocytic cargo
with Tat-1 (Chen et al. 2010).
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| Accession Number: | H2L0H3 |
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| Protein Name: | CDC50 family protein chat-1 |
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| Length: | 348 |
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| Molecular Weight: | 38572.00 |
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| Species: | Caenorhabditis elegans [6239] |
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| Number of TMSs: | 2 |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
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| Substrate |
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1: MPPRDAVPTS TQVSGIGADG VQTEKVLKNR PKASALRQQK LPAWQPILTA TTVIPTVFVI
61: GAIFLPIGVF LFIASDAVSE FTVEYTNCLS PCQLQINLPN AFDGDVFLYY NLENYYQNHR
121: RYVKSRNDQQ YLGDLTNVKD CAPFDIDPAT KKPIAPCGAI ANSIFNDTFT LAHRADTGIV
181: TMVPVTTQGV IWNVDKDRKF KNPPLNDGNL CDAFNNTTKP PNWSKNPCEV GGFENVDFIV
241: WMRTAALPYF KKLWRIVDRT TNPLFSNGLP QGTYILTVEN NYPVQSFGGK KEFVISTTSW
301: AGGKNSFLGI AYLVVGSLAI VLGVVFIVIH MKFGHSMNEL SNVSEIHH