8.A.40.1.15
The tetraspan 24 protein, TSPAN24 or CD151 of 254 aas and 4 TMSs in a 3 + 1 TM arrangement. It is essential for the proper assembly of the glomerular and tubular basement membranes in kidney, and also functions in egg-sperm interactions, possibly in cell-cell fusion, where oocyte CD151 interacts with CD49 in the sperm (Sabetian et al. 2014).
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| Accession Number: | P48509 |
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| Protein Name: | CD151 antigen |
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| Length: | 253 |
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| Molecular Weight: | 28295.00 |
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| Species: | Homo sapiens (Human) [9606] |
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| Number of TMSs: | 4 |
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| Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
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| Substrate |
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1: MGEFNEKKTT CGTVCLKYLL FTYNCCFWLA GLAVMAVGIW TLALKSDYIS LLASGTYLAT
61: AYILVVAGTV VMVTGVLGCC ATFKERRNLL RLYFILLLII FLLEIIAGIL AYAYYQQLNT
121: ELKENLKDTM TKRYHQPGHE AVTSAVDQLQ QEFHCCGSNN SQDWRDSEWI RSQEAGGRVV
181: PDSCCKTVVA LCGQRDHASN IYKVEGGCIT KLETFIQEHL RVIGAVGIGI ACVQVFGMIF
241: TCCLYRSLKL EHY