8.A.40.1.22
Tetraspan-9, Tspan9, of 239 aas and 4 TMSs. Plays a role in aggregation and secretion induced by the platelet collagen receptor, GPVI, despite normal surface GPVI expression levels. This is because Tspan9 plays a role in platelet activation by regulating GPVI membrane dynamics (Haining et al. 2017).
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| Accession Number: | O75954 |
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| Protein Name: | Tetraspanin-9 |
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| Length: | 239 |
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| Molecular Weight: | 26779.00 |
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| Species: | Homo sapiens (Human) [9606] |
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| Number of TMSs: | 4 |
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| Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
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| Substrate |
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1: MARGCLCCLK YMMFLFNLIF WLCGCGLLGV GIWLSVSQGN FATFSPSFPS LSAANLVIAI
61: GTIVMVTGFL GCLGAIKENK CLLLSFFIVL LVILLAELIL LILFFVYMDK VNENAKKDLK
121: EGLLLYHTEN NVGLKNAWNI IQAEMRCCGV TDYTDWYPVL GENTVPDRCC MENSQGCGRN
181: ATTPLWRTGC YEKVKMWFDD NKHVLGTVGM CILIMQILGM AFSMTLFQHI HRTGKKYDA