8.A.47.1.1
Neuropilin and tolloid-like 1 (Neto1 or BTCL1) protein of 533 aas and 2 TMSs (Copits and Swanson 2012; Howe 2014). It is involved in the development and/or maintenance of neuronal circuitry and is an accessory subunit of the neuronal N-methyl-D-aspartate receptor (NMDAR), critical for maintaining the abundance of GRIN2A-containing NMDARs in the postsynaptic density. It also regulates long-term NMDA receptor-dependent synaptic plasticity and cognition, at least in the context of spatial learning and memory (Howe 2014). It is involved in the development and/or maintenance of neuronal circuitry and is an accessory subunit of the neuronal N-methyl-D-aspartate receptor (NMDAR), critical for maintaining the abundance of GRIN2A-containing NMDARs in the postsynaptic density. It also regulates long-term NMDA receptor-dependent synaptic plasticity and cognition, at least in the context of spatial learning and memory (Michishita et al. 2004).