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8.A.56.1.5 TMEM181 of 612 aas and 8 TMSs in a 1 + 7 TMS arrangement. It mediates the action of cytolethal distending toxins (CDT), which are secreted by many pathogenic bacteria. Expression levels of TMEM181 are rate-limiting for intoxication (Carette et al. 2009).
Accession Number:	Q9P2C4
Protein Name:	Transmembrane protein 181
Length:	612
Molecular Weight:	69325.00
Species:	Homo sapiens (Human) [9606]
Number of TMSs:	8
Location¹ / Topology² / Orientation³:	Membrane¹ / Multi-pass membrane protein²
Substrate

UniProt (Universal Protein Resource)
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FASTA formatted sequence

1:	MGAAPSPTQA SSRGGGPGPP APTRAVSSSS RARGGALSAL GPSPARPLTT SPAPAPPPRS 
61:	RPARQQPDPQ CWEKRGGAGG DTKGGAAGPG PGRLRGMDAE YPAFEPPLCS ELKHLCRRLR 
121:	EAYRELKEDL TPFKDDRYYR LAPMRLYTLS KRHFVLVFVV FFICFGLTIF VGIRGPKVIQ 
181:	TSAANFSLNN SKKLKPIQIL SNPLSTYNQQ LWLTCVVELD QSKETSIKTS FPMTVKVDGV 
241:	AQDGTTMYIH NKVHNRTRTL TCAGKCAEII VAHLGYLNYT QYTVIVGFEH LKLPIKGMNF 
301:	TWKTYNPAFS RLEIWFRFFF VVLTFIVTCL FAHSLRKFSM RDWGIEQKWM SVLLPLLLLY 
361:	NDPFFPLSFL VNSWLPGMLD DLFQSMFLCA LLLFWLCVYH GIRVQGERKC LTFYLPKFFI 
421:	VGLLWLASVT LGIWQTVNEL HDPMYQYRVD TGNFQGMKVF FMVVAAVYIL YLLFLIVRAC 
481:	SELRHMPYVD LRLKFLTALT FVVLVISIAI LYLRFGAQVL QDNFVAELST HYQNSAEFLS 
541:	FYGLLNFYLY TLAFVYSPSK NALYESQLKD NPAFSMLNDS DDDVIYGSDY EEMPLQNGQA 
601:	IRAKYKEESD SD

8.A.56.1.5
TMEM181 of 612 aas and 8 TMSs in a 1 + 7 TMS arrangement. It mediates the action of cytolethal distending toxins (CDT), which are secreted by many pathogenic bacteria. Expression levels of TMEM181 are rate-limiting for intoxication (Carette et al. 2009).

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8.A.56.1.5TMEM181 of 612 aas and 8 TMSs in a 1 + 7 TMS arrangement. It mediates the action of cytolethal distending toxins (CDT), which are secreted by many pathogenic bacteria. Expression levels of TMEM181 are rate-limiting for intoxication (Carette et al. 2009).

Cross database links:

External Searches:

Analyze:

8.A.56.1.5
TMEM181 of 612 aas and 8 TMSs in a 1 + 7 TMS arrangement. It mediates the action of cytolethal distending toxins (CDT), which are secreted by many pathogenic bacteria. Expression levels of TMEM181 are rate-limiting for intoxication (Carette et al. 2009).