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8.A.57.1.1 The Wolfram syndrom 1 protein, Wolframin of 890 aas and 10 TMSs. Regulates the SERCA Ca²⁺ ATPase in the endoplasmic reticulum (Zatyka et al. 2015) as well as subunits of the V-type ATPase. See family description for more details.
Accession Number:	O76024
Protein Name:	Wolframin
Length:	890
Molecular Weight:	100292.00
Species:	Homo sapiens (Human) [9606]
Number of TMSs:	9
Location¹ / Topology² / Orientation³:	Endoplasmic reticulum membrane¹ / Multi-pass membrane protein²
Substrate

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MDSNTAPLGP SCPQPPPAPQ PQARSRLNAT ASLEQERSER PRAPGPQAGP GPGVRDAAAP 
61:	AEPQAQHTRS RERADGTGPT KGDMEIPFEE VLERAKAGDP KAQTEVGKHY LQLAGDTDEE 
121:	LNSCTAVDWL VLAAKQGRRE AVKLLRRCLA DRRGITSENE REVRQLSSET DLERAVRKAA 
181:	LVMYWKLNPK KKKQVAVAEL LENVGQVNEH DGGAQPGPVP KSLQKQRRML ERLVSSESKN 
241:	YIALDDFVEI TKKYAKGVIP SSLFLQDDED DDELAGKSPE DLPLRLKVVK YPLHAIMEIK 
301:	EYLIDMASRA GMHWLSTIIP THHINALIFF FIVSNLTIDF FAFFIPLVIF YLSFISMVIC 
361:	TLKVFQDSKA WENFRTLTDL LLRFEPNLDV EQAEVNFGWN HLEPYAHFLL SVFFVIFSFP 
421:	IASKDCIPCS ELAVITGFFT VTSYLSLSTH AEPYTRRALA TEVTAGLLSL LPSMPLNWPY 
481:	LKVLGQTFIT VPVGHLVVLN VSVPCLLYVY LLYLFFRMAQ LRNFKGTYCY LVPYLVCFMW 
541:	CELSVVILLE STGLGLLRAS IGYFLFLFAL PILVAGLALV GVLQFARWFT SLELTKIAVT 
601:	VAVCSVPLLL RWWTKASFSV VGMVKSLTRS SMVKLILVWL TAIVLFCWFY VYRSEGMKVY 
661:	NSTLTWQQYG ALCGPRAWKE TNMARTQILC SHLEGHRVTW TGRFKYVRVT DIDNSAESAI 
721:	NMLPFFIGDW MRCLYGEAYP ACSPGNTSTA EEELCRLKLL AKHPCHIKKF DRYKFEITVG 
781:	MPFSSGADGS RSREEDDVTK DIVLRASSEF KSVLLSLRQG SLIEFSTILE GRLGSKWPVF 
841:	ELKAISCLNC MAQLSPTRRH VKIEHDWRST VHGAVKFAFD FFFFPFLSAA

8.A.57.1.1
The Wolfram syndrom 1 protein, Wolframin of 890 aas and 10 TMSs. Regulates the SERCA Ca²⁺ ATPase in the endoplasmic reticulum (Zatyka et al. 2015) as well as subunits of the V-type ATPase. See family description for more details.

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8.A.57.1.1The Wolfram syndrom 1 protein, Wolframin of 890 aas and 10 TMSs. Regulates the SERCA Ca2+ ATPase in the endoplasmic reticulum (Zatyka et al. 2015) as well as subunits of the V-type ATPase. See family description for more details.

Cross database links:

External Searches:

Analyze:

8.A.57.1.1
The Wolfram syndrom 1 protein, Wolframin of 890 aas and 10 TMSs. Regulates the SERCA Ca²⁺ ATPase in the endoplasmic reticulum (Zatyka et al. 2015) as well as subunits of the V-type ATPase. See family description for more details.