8.A.58.1.4
IFITM5, Bril, Fragilis4 of 134 aas and 2 TMSs. The human ortholog shows abnormalities comprised deficient TGFbeta and P53 signal pathways as well as cell cycle pathway activation, and a potentially new driver mutation in the interferon induced transmembrane protein 5 (IFITM5) (Sun et al. 2023).
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| Accession Number: | O88728 |
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| Protein Name: | Interferon-induced transmembrane protein 5 |
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| Length: | 134 |
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| Molecular Weight: | 14667.00 |
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| Species: | Mus musculus (Mouse) [10090] |
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| Number of TMSs: | 2 |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
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| Substrate |
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1: MDTSYPREDP RAPSSRKADA AAHTALSMGT PGPTPRDHML WSVFSTMYLN LCCLGFLALV
61: HSVKARDQKM AGNLEAARQY GSKAKCYNIL AAMWTLVPPL LLLGLVVTGA LHLSKLAKDS
121: AAFFSTKFDE EDYN