8.A.61.1.2
Cornichon, endoplasmic reticulum protein of 144 aas and 3 TMSs. Involved in transport and secretion of TGFα family proteins (Castro et al. 2007). The gating of AMPARs occurs in milliseconds, precisely controlled by a variety of auxiliary subunits, including cornichon and stargazin, that are expressed differentially in the brain (Hawken et al. 2017).
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| Accession Number: | O95406 |
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| Protein Name: | Protein cornichon homolog 1 |
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| Length: | 144 |
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| Molecular Weight: | 16699.00 |
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| Species: | Homo sapiens (Human) [9606] |
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| Number of TMSs: | 3 |
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| Location1 / Topology2 / Orientation3: |
Endoplasmic reticulum membrane1 / Multi-pass membrane protein2 |
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| Substrate |
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1: MAFTFAAFCY MLALLLTAAL IFFAIWHIIA FDELKTDYKN PIDQCNTLNP LVLPEYLIHA
61: FFCVMFLCAA EWLTLGLNMP LLAYHIWRYM SRPVMSGPGL YDPTTIMNAD ILAYCQKEGW
121: CKLAFYLLAF FYYLYGMIYV LVSS