8.A.61.1.9
Cornichon homolog (CNIH1) protein of 146 aas and 3 TMSs. There are 5 paralogs in A. thaiana. CNIH proteins regulate glutamate-like receptors (GLRs). AtGLRs interact with AtCNIH pairs, yielding specific intracellular localizations. AtCNIHs further trigger AtGLR activity in mammalian cells without a ligand. Thus, a regulatory mechanism underlies Ca2+ homeostasis by sorting and activation of AtGLRs by AtCNIHs (Wudick et al. 2018).
|
| Accession Number: | Q9C7D7 |
|---|
| Protein Name: | Protein cornichon homolog 1 |
|---|
| Length: | 146 |
|---|
| Molecular Weight: | 17368.00 |
|---|
| Species: | Arabidopsis thaliana (Mouse-ear cress) [3702] |
|---|
| Number of TMSs: | 3 |
|---|
| Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
|---|
| Substrate |
|
|---|
1: MAWDLFLWIV SFFVSLALVA SVFYQVICLT DLEADYLNPF ETSTRINRLV IPEFILQGSL
61: CLLFLLTWHW VFFLVAVPVT VYHAMLYKER RYLIDVTEVF RGISFEKKLR YTKLGFYVFL
121: FIMVVFRLTL SAVYSFTEDD DLLHLF