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8.A.62.1.1
Tmub1 or HOPS of 246 aas and 3 TMSs in a 1 (N-terminal) + 2 (C-terminal) TMS arrangement (Yang et al. 2008). It functions in a complex with BORC (196 aas; Q969J3) and ARL8 (179 aas; Q96KC2), functioning in cholesterol egress from lysosomes (Anderson et al. 2022; see also TC# 2.A.6.6.1.1).

Accession Number:Q9BVT8
Protein Name:Transmembrane and ubiquitin-like domain-containing protein 1
Length:246
Molecular Weight:26261.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:3
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MTLIEGVGDE VTVLFSVLAC LLVLALAWVS THTAEGGDPL PQPSGTPTPS QPSAAMAATD 
61:	SMRGEAPGAE TPSLRHRGQA AQPEPSTGFT ATPPAPDSPQ EPLVLRLKFL NDSEQVARAW 
121:	PHDTIGSLKR TQFPGREQQV RLIYQGQLLG DDTQTLGSLH LPPNCVLHCH VSTRVGPPNP 
181:	PCPPGSEPGP SGLEIGSLLL PLLLLLLLLL WYCQIQYRPF FPLTATLGLA GFTLLLSLLA 
241:	FAMYRP