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8.A.66.1.7 Dystrobrevin α of 743 aas and possibly two close TMSs near the N-terminus. May play roles in the formation and stability of synapses as well as in the clustering of nicotinic acetylcholine receptors. It may also play a role in Meniere's Disease (Lopez-Escamez et al. 2018).
Accession Number:	Q9Y4J8
Protein Name:	Dystrobrevin alpha
Length:	743
Molecular Weight:	83901.00
Species:	Homo sapiens (Human) [9606]
Number of TMSs:	1
Location¹ / Topology² / Orientation³:	Cytoplasm¹
Substrate

Structure:
2E5R

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MIEDSGKRGN TMAERRQLFA EMRAQDLDRI RLSTYRTACK LRFVQKKCNL HLVDIWNVIE 
61:	ALRENALNNL DPNTELNVSR LEAVLSTIFY QLNKRMPTTH QIHVEQSISL LLNFLLAAFD 
121:	PEGHGKISVF AVKMALATLC GGKIMDKLRY IFSMISDSSG VMVYGRYDQF LREVLKLPTA 
181:	VFEGPSFGYT EQSARSCFSQ QKKVTLNGFL DTLMSDPPPQ CLVWLPLLHR LANVENVFHP 
241:	VECSYCHSES MMGFRYRCQQ CHNYQLCQDC FWRGHAGGSH SNQHQMKEYT SWKSPAKKLT 
301:	NALSKSLSCA SSREPLHPMF PDQPEKPLNL AHIVDTWPPR PVTSMNDTLF SHSVPSSGSP 
361:	FITRSSPPKD SEVEQNKLLA RAAPAFLKGK GIQYSLNVAD RLADEHVLIG LYVNMLRNNP 
421:	SCMLESSNRL DEEHRLIARY AARLAAESSS SQPPQQRSAP DISFTIDANK QQRQLIAELE 
481:	NKNREILQEI QRLRLEHEQA SQPTPEKAQQ NPTLLAELRL LRQRKDELEQ RMSALQESRR 
541:	ELMVQLEGLM KLLKTQGAGS PRSSPSHTIS RPIPMPIRSA SACSTPTHTP QDSLTGVGGD 
601:	VQEAFAQSSR RNLRNDLLVA ADSITNTMSS LVKELNSEVG SETESNVDSE FARTQFEDLV 
661:	PSPTSEKAFL AQIHARKPGY IHSGATTSTM RGDMVTEDAD PYVQPEDENY ENDSVRQLEN 
721:	ELQMEEYLKQ KLQDEAYQVS LQG

8.A.66.1.7
Dystrobrevin α of 743 aas and possibly two close TMSs near the N-terminus. May play roles in the formation and stability of synapses as well as in the clustering of nicotinic acetylcholine receptors. It may also play a role in Meniere's Disease (Lopez-Escamez et al. 2018).

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8.A.66.1.7Dystrobrevin α of 743 aas and possibly two close TMSs near the N-terminus. May play roles in the formation and stability of synapses as well as in the clustering of nicotinic acetylcholine receptors. It may also play a role in Meniere's Disease (Lopez-Escamez et al. 2018).

Cross database links:

External Searches:

Analyze:

8.A.66.1.7
Dystrobrevin α of 743 aas and possibly two close TMSs near the N-terminus. May play roles in the formation and stability of synapses as well as in the clustering of nicotinic acetylcholine receptors. It may also play a role in Meniere's Disease (Lopez-Escamez et al. 2018).