8.A.87.1.47
CTGF (CON2, HCS24, IGFBP80) protein of 349 aas and 2 - 4 TMSs, N-terminal between residues 1 and 140. It regulates mineralization in human mature chondrocyte by controlling Pit-1 (Xiao et al. 2024). It mediates heparin- and divalent cation-dependent cell adhesion in many
cell types including fibroblasts, myofibroblasts, endothelial and
epithelial cells (Nakanishi et al. 2000).
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| Accession Number: | P29279 |
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| Protein Name: | CCN family member 2 |
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| Length: | 349 |
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| Molecular Weight: | 38091.00 |
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| Species: | Homo sapiens (Human) [9606] |
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| Location1 / Topology2 / Orientation3: |
Secreted1 |
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| Substrate |
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1: MTAASMGPVR VAFVVLLALC SRPAVGQNCS GPCRCPDEPA PRCPAGVSLV LDGCGCCRVC
61: AKQLGELCTE RDPCDPHKGL FCHFGSPANR KIGVCTAKDG APCIFGGTVY RSGESFQSSC
121: KYQCTCLDGA VGCMPLCSMD VRLPSPDCPF PRRVKLPGKC CEEWVCDEPK DQTVVGPALA
181: AYRLEDTFGP DPTMIRANCL VQTTEWSACS KTCGMGISTR VTNDNASCRL EKQSRLCMVR
241: PCEADLEENI KKGKKCIRTP KISKPIKFEL SGCTSMKTYR AKFCGVCTDG RCCTPHRTTT
301: LPVEFKCPDG EVMKKNMMFI KTCACHYNCP GDNDIFESLY YRKMYGDMA