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8.A.88.2.7
Protein disulfide-isomerase A3, PDIA3, ERP57, ERP60, GRP58, of 505 aas and 1 N-terminal TMS. Protein translocation in the ER via the general secretory pathway (3.A.5) acquires substrate selectivity through ER stress-induced reassembly of translocon auxiliary components including calnexin and ERP57 (Lee et al. 2020).

Accession Number:P30101
Protein Name:Protein disulfide-isomerase A3
Length:505
Molecular Weight:56782.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Endoplasmic reticulum1
Substrate protein

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MRLRRLALFP GVALLLAAAR LAAASDVLEL TDDNFESRIS DTGSAGLMLV EFFAPWCGHC 
61:	KRLAPEYEAA ATRLKGIVPL AKVDCTANTN TCNKYGVSGY PTLKIFRDGE EAGAYDGPRT 
121:	ADGIVSHLKK QAGPASVPLR TEEEFKKFIS DKDASIVGFF DDSFSEAHSE FLKAASNLRD 
181:	NYRFAHTNVE SLVNEYDDNG EGIILFRPSH LTNKFEDKTV AYTEQKMTSG KIKKFIQENI 
241:	FGICPHMTED NKDLIQGKDL LIAYYDVDYE KNAKGSNYWR NRVMMVAKKF LDAGHKLNFA 
301:	VASRKTFSHE LSDFGLESTA GEIPVVAIRT AKGEKFVMQE EFSRDGKALE RFLQDYFDGN 
361:	LKRYLKSEPI PESNDGPVKV VVAENFDEIV NNENKDVLIE FYAPWCGHCK NLEPKYKELG 
421:	EKLSKDPNIV IAKMDATAND VPSPYEVRGF PTIYFSPANK KLNPKKYEGG RELSDFISYL 
481:	QREATNPPVI QEEKPKKKKK AQEDL