8.B.1.1.7
AahII; neurotoxin 2 of 85 aas. Scorpion α-toxins bind voltage-independently at site-3 of sodium channels
(Nav) and inhibit the inactivation of the activated channels, thereby
blocking neuronal transmission. This toxin is active against mammals.
|
| Accession Number: | P01484 |
|---|
| Protein Name: | Alpha-mammal toxin AaH2 |
|---|
| Length: | 85 |
|---|
| Molecular Weight: | 9548.00 |
|---|
| Species: | Androctonus australis (Sahara scorpion) [6858] |
|---|
| Location1 / Topology2 / Orientation3: |
Secreted1 |
|---|
| Substrate |
|
|---|
1: MNYLVMISLA LLFVTGVESV KDGYIVDDVN CTYFCGRNAY CNEECTKLKG ESGYCQWASP
61: YGNACYCYKL PDHVRTKGPG RCHGR