8.B.16.2.1
Gamma-conotoxin PnVIIA of 80 aas and 1 TMS. It may act on voltage-gated non-specific cation
pacemaker channels (HCN). It triggers depolarization and firing of action
potential bursts in the caudodorsal neurons of lymnaea. This effect is
due to activation or enhancement of a slow inward cation current that
may underlie endogenous bursting activity of these neurons (Fainzilber et al. 1998).
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| Accession Number: | P56711 |
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| Protein Name: | Gamma-conotoxin PnVIIA |
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| Length: | 80 |
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| Molecular Weight: | 9189.00 |
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| Species: | Conus pennaceus (Feathered cone) [37335] |
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| Location1 / Topology2 / Orientation3: |
Secreted1 |
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| Substrate |
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1: MEKLTILLLV AAVLMSTQAQ NQEQRQQAKI NFLSKRKPSA ERWRRDCTSW FGRCTVNSEC
61: CSNSCDQTYC ELYAFPSFGA