8.B.16.3.1
Alpha-conotoxin-like Rt20.2 of 92 aas with 1 N-terminal TMS. Alpha-conotoxins act on postsynaptic membranes,;they bind to the nicotinic acetylcholine receptors (nAChR) and thus
inhibit them. This toxin specifically blocks mammalian neuronal nAChR of
the alpha-7/CHRNA7, alpha-3-beta-2/CHRNA3-CHRNB2 and
alpha-4-beta-2/CHRNA4-CHRNB2 subtypes.α-conotoxin
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| Accession Number: | P0CE35 |
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| Protein Name: | Alpha-conotoxin-like Rt20.2 |
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| Length: | 92 |
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| Molecular Weight: | 10364.00 |
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| Species: | Conus rattus (Rat cone) [72283] |
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| Number of TMSs: | 1 |
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| Location1 / Topology2 / Orientation3: |
Secreted1 |
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| Substrate |
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1: MPKLEMMLLV LLILPLSYFS AAGGQVVQGD LHSDVLARYL QRGDRDAREC QVNTPGSRWG
61: KCCLNRMCGP MCCPESHCYC IYHRRRGHGC SC