8.B.21.1.9 Kappa conotoxin BTx or BeTx of 70 aas and 1 N-terminal TMS. It is a modulator of potassium channels, specifically
up-modulating the calcium and voltage-gated BK channels. It has no effect on
single channel conductance, but increases the open probability of BK
channels (Fan et al. 2003).
|
Accession Number: | Q9U3Z3 |
Protein Name: | Kappa-conotoxin BtX |
Length: | 70 |
Molecular Weight: | 7900.00 |
Species: | Conus betulinus (Beech cone) [89764] |
Number of TMSs: | 1 |
Location1 / Topology2 / Orientation3: |
Secreted1 |
Substrate |
|
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1: MMFRVTSVGC LLLVIVFLNL VVPTSACRAE GTYCENDSQC CLNECCWGGC GHPCRHPGKR
61: SKLQEFFRQR