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8.B.32.1.4
α-Conotoxin LvIA of 37 aas and 1 TMS.  This toxin blocks alpha-3-beta-2/CHRNA3-CHRNB2 nAChR with high selectivity (IC50=8.7 nM (on rat) and 17.5 (on human)) (Luo et al. 2014).

Accession Number:L8BU87
Protein Name:Alpha-conotoxin LvIA
Length:37
Molecular Weight:3841.00
Species:Conus lividus (Livid cone) [89426]
Location1 / Topology2 / Orientation3: Secreted1
Substrate

Cross database links:

Structure:
2MDQ   5XGL     

External Searches:

  • Search: DB with
  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
  • CDD Search (Conserved Domain Database)
  • Search COGs (Clusters of Orthologous Groups of proteins)
  • 2° Structure (Network Protein Sequence Analysis)

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	FRGRDAAAKA SGLVGLTDRR GCCSHPACNV DHPEICG