8.B.6.1.9
Delta (δ)-amaurobitoxin-Pl1b of 27 aas and 0 TMSs. Insecticidal toxin. Lethal to lepidopteran larvae. No adverse affect is observed
when intracerebroventricularly injected in mice at a dose of 0.2 μg but
causes reversible paralysis of legs when injected
intracerebroventricularly in mice at a dose of 2.0 μg. Binds to site 4
of insect voltage-gated sodium channel (Nav) and inhibits channel
inactivation (Corzo et al. 2000; Corzo et al. 2005).
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| Accession Number: | P83257 |
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| Protein Name: | Delta-amaurobitoxin-Pl1b |
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| Length: | 37 |
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| Molecular Weight: | 4124.00 |
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| Species: | Pireneitega luctuosa (Tangled nest spider) [185217] |
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| Location1 / Topology2 / Orientation3: |
Secreted1 |
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| Substrate |
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1: ACVGDGQRCA SWSGPYCCDG YYCSCRSMPY CRCRNNS