8.B.8.1.7
Potassium channel toxin alpha-KTx 6.21; Urotoxin, of 62 aas. Blocker of voltage-gated potassium channels. It has
highest activity on human voltage-gated potassium channel Kv1.2/KCNA2
channels, with an IC50 of 160 pM, whereas its affinity for other channels tested was in the nanomolar range (Luna-Ramírez et al. 2014).
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| Accession Number: | P0DL37 |
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| Protein Name: | Potassium channel toxin alpha-KTx 6.21 |
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| Length: | 62 |
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| Molecular Weight: | 6793.00 |
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| Species: | Urodacus yaschenkoi (Inland robust scorpion) [1273102] |
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| Number of TMSs: | 1 |
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| Location1 / Topology2 / Orientation3: |
Secreted1 |
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| Substrate |
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1: MNAKLIYLLL VVTTMMLTFD TTQAGDIKCS GTRQCWGPCK KQTTCTNSKC MNGKCKCYGC
61: VG