TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


9.A.14.1.17
Bovine rhodopsin of 348 aas and 7 TMSs.  It is the photoreceptor required for image-forming vision at low light intensity. Also required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins (Singhal et al. 2016; Deupi et al. 2012). The x-ray structure has been determined at high resolution, and the folding and oligomerization (Okada and Palczewski 2001; Brown and Ernst 2017). This protein is 93% identical to the human ortholog (TC# 9.A.14.1.2).

Accession Number:P02699
Protein Name:Rhodopsin
Length:348
Molecular Weight:39008.00
Species:Bos taurus (Bovine) [9913]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate

Cross database links:

Structure:
1EDS   1EDV   1EDW   1EDX   1F88   1FDF   1GZM   1HZX   1JFP   1L9H   [...more]

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MNGTEGPNFY VPFSNKTGVV RSPFEAPQYY LAEPWQFSML AAYMFLLIML GFPINFLTLY 
61:	VTVQHKKLRT PLNYILLNLA VADLFMVFGG FTTTLYTSLH GYFVFGPTGC NLEGFFATLG 
121:	GEIALWSLVV LAIERYVVVC KPMSNFRFGE NHAIMGVAFT WVMALACAAP PLVGWSRYIP 
181:	EGMQCSCGID YYTPHEETNN ESFVIYMFVV HFIIPLIVIF FCYGQLVFTV KEAAAQQQES 
241:	ATTQKAEKEV TRMVIIMVIA FLICWLPYAG VAFYIFTHQG SDFGPIFMTI PAFFAKTSAV 
301:	YNPVIYIMMN KQFRNCMVTT LCCGKNPLGD DEASTTVSKT ETSQVAPA