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9.A.14.10.5
G-protein coupled receptor, NPSR1, for neuropeptide S (NPS) and promotes mobilization of intracellular Ca2+ stores (Bernier et al. 2006). It also inhibits cell growth in response to NPS binding (Vendelin et al. 2005). It is involved in the pathogenesis of asthma and other IgE-mediated diseases (Xu et al. 2004; Bernier et al. 2006).

Accession Number:Q6W5P4
Protein Name:Neuropeptide S receptor
Length:371
Molecular Weight:42687.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Cytoplasm1
Substrate

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  • BLAST ExPASy (Swiss Institute of Bioinformatics (SIB) BLAST)
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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MPANFTEGSF DSSGTGQTLD SSPVACTETV TFTEVVEGKE WGSFYYSFKT EQLITLWVLF 
61:	VFTIVGNSVV LFSTWRRKKK SRMTFFVTQL AITDSFTGLV NILTDINWRF TGDFTAPDLV 
121:	CRVVRYLQVV LLYASTYVLV SLSIDRYHAI VYPMKFLQGE KQARVLIVIA WSLSFLFSIP 
181:	TLIIFGKRTL SNGEVQCWAL WPDDSYWTPY MTIVAFLVYF IPLTIISIMY GIVIRTIWIK 
241:	SKTYETVISN CSDGKLCSSY NRGLISKAKI KAIKYSIIII LAFICCWSPY FLFDILDNFN 
301:	LLPDTQERFY ASVIIQNLPA LNSAINPLIY CVFSSSISFP CREQRSQDSR MTFRERTERH 
361:	EMQILSKPEF I