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9.A.14.13.20 Prosaposin receptor, Gpr37 of 613 aas and 7 TMSs. Receptor for the neuroprotective and glioprotective factor, prosaposin. Ligand binding induces endocytosis, followed by an ERK phosphorylation cascade (Meyer et al. 2013).
Accession Number:	O15354
Protein Name:	Prosaposin receptor GPR37
Length:	613
Molecular Weight:	67114.00
Species:	Homo sapiens (Human) [9606]
Number of TMSs:	7
Location¹ / Topology² / Orientation³:	Cell membrane¹ / Multi-pass membrane protein²
Substrate

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MRAPGALLAR MSRLLLLLLL KVSASSALGV APASRNETCL GESCAPTVIQ RRGRDAWGPG 
61:	NSARDVLRAR APREEQGAAF LAGPSWDLPA APGRDPAAGR GAEASAAGPP GPPTRPPGPW 
121:	RWKGARGQEP SETLGRGNPT ALQLFLQISE EEEKGPRGAG ISGRSQEQSV KTVPGASDLF 
181:	YWPRRAGKLQ GSHHKPLSKT ANGLAGHEGW TIALPGRALA QNGSLGEGIH EPGGPRRGNS 
241:	TNRRVRLKNP FYPLTQESYG AYAVMCLSVV IFGTGIIGNL AVMCIVCHNY YMRSISNSLL 
301:	ANLAFWDFLI IFFCLPLVIF HELTKKWLLE DFSCKIVPYI EVASLGVTTF TLCALCIDRF 
361:	RAATNVQMYY EMIENCSSTT AKLAVIWVGA LLLALPEVVL RQLSKEDLGF SGRAPAERCI 
421:	IKISPDLPDT IYVLALTYDS ARLWWYFGCY FCLPTLFTIT CSLVTARKIR KAEKACTRGN 
481:	KRQIQLESQM NCTVVALTIL YGFCIIPENI CNIVTAYMAT GVSQQTMDLL NIISQFLLFF 
541:	KSCVTPVLLF CLCKPFSRAF MECCCCCCEE CIQKSSTVTS DDNDNEYTTE LELSPFSTIR 
601:	REMSTFASVG THC

9.A.14.13.20
Prosaposin receptor, Gpr37 of 613 aas and 7 TMSs. Receptor for the neuroprotective and glioprotective factor, prosaposin. Ligand binding induces endocytosis, followed by an ERK phosphorylation cascade (Meyer et al. 2013).

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9.A.14.13.20Prosaposin receptor, Gpr37 of 613 aas and 7 TMSs. Receptor for the neuroprotective and glioprotective factor, prosaposin. Ligand binding induces endocytosis, followed by an ERK phosphorylation cascade (Meyer et al. 2013).

Cross database links:

External Searches:

Analyze:

9.A.14.13.20
Prosaposin receptor, Gpr37 of 613 aas and 7 TMSs. Receptor for the neuroprotective and glioprotective factor, prosaposin. Ligand binding induces endocytosis, followed by an ERK phosphorylation cascade (Meyer et al. 2013).