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9.A.14.4.5
Gastric inhibitory polypeptide receptor 

Accession Number:P48546
Protein Name:Gastric inhibitory polypeptide receptor
Length:466
Molecular Weight:53157.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate

Cross database links:

DIP: DIP-46468N
Entrez Gene ID: 2696   
Pfam: PF00002    PF02793   
KEGG: hsa:2696   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0006091 P:generation of precursor metabolites and energy
GO:0007584 P:response to nutrient

References (6)

[1] “Molecular cloning, functional expression, and signal transduction of the GIP-receptor cloned from a human insulinoma.”  Volz A.et.al.   7589426
[2] “Cloning, functional expression, and chromosomal localization of the human pancreatic islet glucose-dependent insulinotropic polypeptide receptor.”  Gremlich S.et.al.   7556958
[3] “Human gastric inhibitory polypeptide receptor: cloning of the gene (GIPR) and cDNA.”  Yamada Y.et.al.   8575774
[4] “The DNA sequence and biology of human chromosome 19.”  Grimwood J.et.al.   15057824
[5] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[6] “Crystal structure of the incretin-bound extracellular domain of a G protein-coupled receptor.”  Parthier C.et.al.   17715056
Structure:
2QKH   4HJ0   6DKJ     

External Searches:

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MTTSPILQLL LRLSLCGLLL QRAETGSKGQ TAGELYQRWE RYRRECQETL AAAEPPSGLA 
61:	CNGSFDMYVC WDYAAPNATA RASCPWYLPW HHHVAAGFVL RQCGSDGQWG LWRDHTQCEN 
121:	PEKNEAFLDQ RLILERLQVM YTVGYSLSLA TLLLALLILS LFRRLHCTRN YIHINLFTSF 
181:	MLRAAAILSR DRLLPRPGPY LGDQALALWN QALAACRTAQ IVTQYCVGAN YTWLLVEGVY 
241:	LHSLLVLVGG SEEGHFRYYL LLGWGAPALF VIPWVIVRYL YENTQCWERN EVKAIWWIIR 
301:	TPILMTILIN FLIFIRILGI LLSKLRTRQM RCRDYRLRLA RSTLTLVPLL GVHEVVFAPV 
361:	TEEQARGALR FAKLGFEIFL SSFQGFLVSV LYCFINKEVQ SEIRRGWHHC RLRRSLGEEQ 
421:	RQLPERAFRA LPSGSGPGEV PTSRGLSSGT LPGPGNEASR ELESYC