| |
---|---|
Accession Number: | P41586 |
Protein Name: | Pituitary adenylate cyclase-activating polypeptide type I receptor |
Length: | 468 |
Molecular Weight: | 53314.00 |
Species: | Homo sapiens (Human) [9606] |
Number of TMSs: | 7 |
Location1 / Topology2 / Orientation3: | Cell membrane1 / Multi-pass membrane protein2 |
Substrate |
Cross database links:
Entrez Gene ID: | 117 |
---|---|
Pfam: | PF00002 PF02793 |
KEGG: | hsa:117 |
Gene Ontology
GO:0005887
C:integral to plasma membrane
GO:0004999
F:vasoactive intestinal polypeptide receptor activity
GO:0007190
P:activation of adenylate cyclase activity
GO:0030154
P:cell differentiation
GO:0007275
P:multicellular organismal development
GO:0048011
P:nerve growth factor receptor signaling pathway
GO:0007283
P:spermatogenesis
| |
References (4)[1] “Molecular cloning and functional expression of a cDNA encoding a human pituitary adenylate cyclase activating polypeptide receptor.” Ogi K.et.al. 7902709 [2] “Complete sequencing and characterization of 21,243 full-length human cDNAs.” Ota T.et.al. 14702039 [3] “Human type I pituitary adenylate cyclase activating polypeptide receptor (ADCYAP1R): localization to chromosome band 7p14 and integration into the cytogenetic, physical and genetic map of chromosome 7.” Stoffel M.et.al. 7851900 [4] “Solution structure and mutational analysis of pituitary adenylate cyclase-activating polypeptide binding to the extracellular domain of PAC1-RS.” Sun C.et.al. 17470806
| |
Structure: | |
External Searches:
|
Analyze:
Predict TMSs (Predict number of transmembrane segments) | ||||
FASTA formatted sequence |
|
1: MAGVVHVSLA ALLLLPMAPA MHSDCIFKKE QAMCLEKIQR ANELMGFNDS SPGCPGMWDN 61: ITCWKPAHVG EMVLVSCPEL FRIFNPDQVW ETETIGESDF GDSNSLDLSD MGVVSRNCTE 121: DGWSEPFPHY FDACGFDEYE SETGDQDYYY LSVKALYTVG YSTSLVTLTT AMVILCRFRK 181: LHCTRNFIHM NLFVSFMLRA ISVFIKDWIL YAEQDSNHCF ISTVECKAVM VFFHYCVVSN 241: YFWLFIEGLY LFTLLVETFF PERRYFYWYT IIGWGTPTVC VTVWATLRLY FDDTGCWDMN 301: DSTALWWVIK GPVVGSIMVN FVLFIGIIVI LVQKLQSPDM GGNESSIYLR LARSTLLLIP 361: LFGIHYTVFA FSPENVSKRE RLVFELGLGS FQGFVVAVLY CFLNGEVQAE IKRKWRSWKV 421: NRYFAVDFKH RHPSLASSGV NGGTQLSILS KSSSQIRMSG LPADNLAT