TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


9.A.18.1.2
Bacteroid development protein, BacA; probably a peptide/bleomycin uptake transporter (Ardissone et al., 2011; Marlow et al., 2009). The bacterial BacA protein is essential for bacteroid differentiation in legumes producing nodule-specific cysteine-rich peptides (NCRs), which induce the terminal differentiation of the bacteria into bacteroids (Haag et al. 2013). This protein and others in this family are homologous to the membrane constituents of 3.A.1.203 family in the ABC superfamily in TCDB.

Accession Number:Q08120
Protein Name:BacA aka RB1125 aka SMB20999
Length:420
Molecular Weight:47849.00
Species:Rhizobium meliloti (Sinorhizobium meliloti) [382]
Number of TMSs:8
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate peptide, bleomycin A2

Cross database links:

RefSeq: NP_437665.1   
Entrez Gene ID: 1237456   
Pfam: PF05992   
BioCyc: SMEL266834:SMB20999-MONOMER   
KEGG: sme:SM_b20999   

Gene Ontology

GO:0009276 C:Gram-negative-bacterium-type cell wall
GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005524 F:ATP binding
GO:0042626 F:ATPase activity, coupled to transmembrane m...
GO:0055085 P:transmembrane transport

References (2)

[1] “A Rhizobium meliloti homolog of the Escherichia coli peptide-antibiotic transport protein SbmA is essential for bacteroid development.”  Glazebrook J.et.al.   8393417
[2] “The complete sequence of the 1,683-kb pSymB megaplasmid from the N2-fixing endosymbiont Sinorhizobium meliloti.”  Finan T.M.et.al.   11481431

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MFQSFFPKPK LFFISSAVWS LLAVLAWYAG GRDIGAYLGL PPLPPGQEPV IGVSVFWSTP 
61:	FLWFYIYYAV VAGLFAAFWF AYSPHRWQYW SVLGTALIIF NTYFSVQVSV AINAWYGPFY 
121:	DLIQQALART APVTAGQLYS GMIGFSGIAF VAVTVGVLNL FFVSHYIFRW RTAMNEFYVA 
181:	HWPRLRHVEG ASQRVQEDTM RFSSTVERLG VGLVSSIMTL IAFLPVLFKF SEQVNVLPIV 
241:	GEIPHALVWA AVFWSVFGTV FLAAVGIKLP GLEFRNQRVE AAYRKELVYG EDHEDRADPI 
301:	TLAQLFDNVR RNYFRLYFHY MYFNIARIFY LQADNLFGTF VLVPAIVAGK LTLGVMNQVL 
361:	NVFGQVRESF QYLVNSWTTI VELLSIYKRL KAFESVLVDE PLPEIDRQFI DAGGKEELAL