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9.A.19.1.1
Lipid and glycosyl phosphatidylinositol intermediate transporter, Arv1 (Villasmil et al., 2011).

Accession Number:Q06541
Protein Name:Protein ARV1
Length:321
Molecular Weight:38194.00
Species:Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Endoplasmic reticulum membrane1 / Multi-pass membrane protein2
Substrate glycosylphosphatidylinositol

Cross database links:

DIP: DIP-5171N
Entrez Gene ID: 850943   
Pfam: PF04161   
KEGG: sce:YLR242C   

Gene Ontology

GO:0005789 C:endoplasmic reticulum membrane
GO:0000139 C:Golgi membrane
GO:0016021 C:integral to membrane
GO:0006897 P:endocytosis
GO:0035621 P:ER to Golgi ceramide transport
GO:0006506 P:GPI anchor biosynthetic process
GO:0032366 P:intracellular sterol transport
GO:0030148 P:sphingolipid biosynthetic process
GO:0035376 P:sterol import

References (5)

[1] “The nucleotide sequence of Saccharomyces cerevisiae chromosome XII.”  Johnston M.et.al.   9169871
[2] “Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae.”  Hu Y.et.al.   17322287
[3] “Identification and characterization of upstream open reading frames (uORF) in the 5' untranslated regions (UTR) of genes in Saccharomyces cerevisiae.”  Zhang Z.et.al.   16012843
[4] “Mutations in yeast ARV1 alter intracellular sterol distribution and are complemented by human ARV1.”  Tinkelenberg A.H.et.al.   11063737
[5] “Yeast cells lacking the ARV1 gene harbor defects in sphingolipid metabolism. Complementation by human ARV1.”  Swain E.et.al.   12145310

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MICITCMRPV DSLYTVYSND HIQLTDCPYC QETVDKYVEI DNVLLFIDLL LLKAGAYRHL 
61:	VFNALELHLS KYPKRKALND CQCLRDYTQA LLFNVKNWFC KYDRLNRLWL LLLSFEIYLT 
121:	WVTEESKYIY YLNRNNNDGK LIMLSKKLPE SFKWDSAIMR NTITSKVFTW SPPIQYLYFA 
181:	SYCILDVSLF HTFTQYFILK KLHWKHYSVS SKDVISYTIL LSYGAKIFPI LMLIWPYDTL 
241:	ISMSIIKWVA NLYIIESLKI VTNLSYWNII KIFISVSLLR YFMVKPILIV FVAKFNFSVI 
301:	KNLIHQEFIL LLQKSGTYLL L