9.A.57.1.3
Extended synaptotagmin T3, EsyT3, of 886 aas and 2 TMSs. See family description for details and references. Contains three C2 Ca2+-binding domains of unknown function but found in many signal transduction proteins. Extended synaptotagmins are Ca2+-dependent lipid transfer proteins found at membrane contact sites. (Yu et al. 2016).
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| Accession Number: | A0FGR9 |
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| Protein Name: | Extended synaptotagmin-3 |
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| Length: | 886 |
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| Molecular Weight: | 100035.00 |
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| Species: | Homo sapiens (Human) [9606] |
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| Number of TMSs: | 2 |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Peripheral membrane protein2 |
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| Substrate |
calcium(2+) |
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1: MRAEEPCAPG APSALGAQRT PGPELRLSSQ LLPELCTFVV RVLFYLGPVY LAGYLGLSIT
61: WLLLGALLWM WWRRNRRGKL GRLAAAFEFL DNEREFISRE LRGQHLPAWI HFPDVERVEW
121: ANKIISQTWP YLSMIMESKF REKLEPKIRE KSIHLRTFTF TKLYFGQKCP RVNGVKAHTN
181: TCNRRRVTVD LQICYIGDCE ISVELQKIQA GVNGIQLQGT LRVILEPLLV DKPFVGAVTV
241: FFLQKPHLQI NWTGLTNLLD APGINDVSDS LLEDLIATHL VLPNRVTVPV KKGLDLTNLR
301: FPLPCGVIRV HLLEAEQLAQ KDNFLGLRGK SDPYAKVSIG LQHFRSRTIY RNLNPTWNEV
361: FEFMVYEVPG QDLEVDLYDE DTDRDDFLGS LQICLGDVMT NRVVDEWFVL NDTTSGRLHL
421: RLEWLSLLTD QEVLTEDHGG LSTAILVVFL ESACNLPRNP FDYLNGEYRA KKLSRFARNK
481: VSKDPSSYVK LSVGKKTHTS KTCPHNKDPV WSQVFSFFVH NVATERLHLK VLDDDQECAL
541: GMLEVPLCQI LPYADLTLEQ RFQLDHSGLD SLISMRLVLR FLQVEERELG SPYTGPEALK
601: KGPLLIKKVA TNQGPKAQPQ EEGPTDLPCP PDPASDTKDV SRSTTTTTSA TTVATEPTSQ
661: ETGPEPKGKD SAKRFCEPIG EKKSPATIFL TVPGPHSPGP IKSPRPMKCP ASPFAWPPKR
721: LAPSMSSLNS LASSCFDLAD ISLNIEGGDL RRRQLGEIQL TVRYVCLRRC LSVLINGCRN
781: LTPCTSSGAD PYVRVYLLPE RKWACRKKTS VKRKTLEPLF DETFEFFVPM EEVKKRSLDV
841: AVKNSRPLGS HRRKELGKVL IDLSKEDLIK GFSQWYELTP NGQPRS