9.A.75.1.4
The neonatal Fc receptor (FcRn), subunit p51 of 365 aas and one C-terminal TMS possibly with one N-terminal TMS as well. Early floral colonization affects intestinal immunoglobulin G uptake in piglets, which may be mediated by the NF-kappaB-FcRn pathway, with FcRn as the actual transmembrane carrier (Peng et al. 2023).
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| Accession Number: | P55899 |
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| Protein Name: | IgG receptor FcRn large subunit p51 |
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| Length: | 365 |
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| Molecular Weight: | 39743.00 |
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| Species: | Homo sapiens (Human) [9606] |
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| Number of TMSs: | 1 |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Single-pass type I membrane protein2 |
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| Substrate |
protein |
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1: MGVPRPQPWA LGLLLFLLPG SLGAESHLSL LYHLTAVSSP APGTPAFWVS GWLGPQQYLS
61: YNSLRGEAEP CGAWVWENQV SWYWEKETTD LRIKEKLFLE AFKALGGKGP YTLQGLLGCE
121: LGPDNTSVPT AKFALNGEEF MNFDLKQGTW GGDWPEALAI SQRWQQQDKA ANKELTFLLF
181: SCPHRLREHL ERGRGNLEWK EPPSMRLKAR PSSPGFSVLT CSAFSFYPPE LQLRFLRNGL
241: AAGTGQGDFG PNSDGSFHAS SSLTVKSGDE HHYCCIVQHA GLAQPLRVEL ESPAKSSVLV
301: VGIVIGVLLL TAAAVGGALL WRRMRSGLPA PWISLRGDDT GVLLPTPGEA QDADLKDVNV
361: IPATA