9.B.102.5.3 Uncharacterized protein of 378 aas and 9 TMSs. The N-terminal 4 TMSs match PmpA (TC# 9.B.102.5.2) while the C-terminal 4 TMSs match PmpB (TC# 9.B.102.5.5) as top hits. Only the central TMS does not show homology. Therefore, the N-terminus of this protein may have its N-terminus inside and its C-terminus outside. Further, this provides evidence that PmpA and PmpB are two parts of a single two subunit transporter. Prodigiosin, which is hypothesized to export prodigiosin in Serratia species, could be the function of this protein since Galdieria species are sensitive to prodigiosin. Thus it could be a prodigiosin efflux pump (Lee et al. 2017).
|
Accession Number: | M2VZH1 |
Protein Name: | Uncharacterized protein |
Length: | 378 |
Molecular Weight: | 39335.00 |
Species: | Galdieria sulphuraria (Red alga) [130081] |
Number of TMSs: | 9 |
Substrate |
Undecylprodigiosin |
---|
1: MPGVIEAICG GLAIGFSVAV NAVLLGRVTG ISGIVGGVLA KQSGLRWRLS FLGGLAGGGW
61: ILRKFLPSTV PIVSGLVSPL RLAAAGLLVG FGTRLGSGCT SGHGVCGLGR LSKRSLVNVL
121: VFMTSGALTA ILTKSVSAYG AGSLVTRDLF TPDKSLLKSF VSFATPAILS LMGIVGASFS
181: LDANIPKKVH EFASPIIGAS TGYLFAIGLG VAGMTNPIQV VRFLDFTRPY WNPSLAFVMG
241: SALVVSLSAF SFLRKRNNRP LLCSQSYIPC AAEVDMNLII GGALFGAGWG LGGFCPGPML
301: VSFFSRPEEQ ANQVVTGAML VGALVYQQLQ KSKETSFQGV PKEDTGKETS RLSESKNNSE
361: SNGYSVQKSD SPSHEEDG