9.B.121.5.1
The AsmA protein of 617aas with 1 N-terminal α-TMS and 20 predicted β-strands. Associates with the inner and the outer membrane, probably spanning the envelope. It influences OMP and LPS insertion, but it is not know if these effects are direct or indirect (Deng and Misra 1996). In Salmonella species, AsmA (Q8Z5G2) activates expression of the marRAB operon and attenuates virulence with poor epithelial invasion (Prieto et al. 2009).
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| Accession Number: | P28249 |
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| Protein Name: | Protein AsmA |
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| Length: | 617 |
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| Molecular Weight: | 68963.00 |
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| Species: | Escherichia coli (strain K12) [83333] |
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| Number of TMSs: | 1 |
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| Location1 / Topology2 / Orientation3: |
Periplasm1 |
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| Substrate |
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1: MRRFLTTLMI LLVVLVAGLS ALVLLVNPND FRDYMVKQVA ARSGYQLQLD GPLRWHVWPQ
61: LSILSGRMSL TAQGASQPLV RADNMRLDVA LLPLLSHQLS VKQVMLKGAV IQLTPQTEAV
121: RSEDAPVAPR DNTLPDLSDD RGWSFDISSL KVADSVLVFQ HEDDEQVTIR NIRLQMEQDP
181: QHRGSFEFSG RVNRDQRDLT ISLNGTVDAS DYPHDLTAAI EQINWQLQGA DLPKQGIQGQ
241: GSFQAQWQES HKRLSFNQIS LTANDSTLSG QAQVTLTEKP EWQLRLQFPQ LNLDNLIPLN
301: ETANGENGAA QQGQSQSTLP RPVISSRIDE PAYQGLQGFT ADILLQASNV RWRGMNFTDV
361: ATQMTNKSGL LEITQLQGKL NGGQVSLPGT LDATSINPRI NFQPRLENVE IGTILKAFNY
421: PISLTGKMSL AGDFSGADID ADAFRHNWQG QAHVEMTDTR MEGMNFQQMI QQAVERNGGD
481: VKAAENFDNV TRLDRFTTDL TLKDGVVTLN DMQGQSPVLA LTGEGMLNLA DQTCDTQFDI
541: RVVGGWNGES KLIDFLKETP VPLRVYGNWQ QLNYSLQVDQ LLRKHLQDEA KRRLNDWAER
601: NKDSRNGKDV KKLLEKM