TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


9.B.123.1.1
TM7SF1 (Called the G-protein-coupled receptor, GPR137B). Co-localizes with LAMP2 (TC#9.A.16.1.2) (Gao et al., 2012). May belong to the WbaP (RfbP) Undecaprenyl phosphate galactose phosphotransferase family (Patel et al., 2012).

Accession Number:O60478
Protein Name:Integral membrane protein GPR137B
Length:399
Molecular Weight:45599.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:7
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate

Cross database links:

Entrez Gene ID: 7107   
KEGG: hsa:7107    hsa:7107   

Gene Ontology

GO:0005887 C:integral to plasma membrane
GO:0005624 C:membrane fraction

References (6)

[1] “Cloning and characterization of a novel gene (TM7SF1) encoding a putative seven-pass transmembrane protein that is upregulated during kidney development.”  Spangenberg C.et.al.   9521871
[2] “The DNA sequence and biological annotation of human chromosome 1.”  Gregory S.G.et.al.   16710414
[3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334
[4] “Cloning and characterization of a novel gene (TM7SF1) encoding a putative seven-pass transmembrane protein that is upregulated during kidney development.”  Spangenberg C.et.al.   9521871
[5] “The DNA sequence and biological annotation of human chromosome 1.”  Gregory S.G.et.al.   16710414
[6] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”  The MGC Project Teamet.al.   15489334

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MRPERPRPRG SAPGPMETPP WDPARNDSLP PTLTPAVPPY VKLGLTVVYT VFYALLFVFI 
61:	YVQLWLVLRY RHKRLSYQSV FLFLCLFWAS LRTVLFSFYF KDFVAANSLS PFVFWLLYCF 
121:	PVCLQFFTLT LMNLYFTQVI FKAKSKYSPE LLKYRLPLYL ASLFISLVFL LVNLTCAVLV 
181:	KTGNWERKVI VSVRVAINDT LFVLCAVSLS ICLYKISKMS LANIYLESKG SSVCQVTAIG 
241:	VTVILLYTSR ACYNLFILSF SQNKSVHSFD YDWYNVSDQA DLKNQLGDAG YVLFGVVLFV 
301:	WELLPTTLVV YFFRVRNPTK DLTNPGMVPS HGFSPRSYFF DNPRRYDSDD DLAWNIAPQG 
361:	LQGGFAPDYY DWGQQTNSFL AQAGTLQDST LDPDKPSLG