TCID | Name | Domain | Kingdom/Phylum | Protein(s) |
---|---|---|---|---|
9.B.157.1.1 | The MreBCD complex which forms an essential membrane associated complex. MreD is a 5 TMS protein resembling members of TC family with sequence similarity to the integral membrane transport protein listed under TC# 3.A.1.26.10. | Bacteria |
Bacillota | MreBCD of Bacillus subtilis MreB, 337 aas, (Q01465) MreC, 290 aas, (Q01466) MreD, 172 aas, (Q01467) |
9.B.157.1.2 | The MreBCD complex. | Bacteria |
Bacillota | MreBCD of Bacillus halodurans MreB, 346 aas (Q9K8H5) MreC, 293 aas (Q9K8H6) MreD, 174 aas (Q9K8H7) |
9.B.157.1.3 | Cell shape determining complex, MreBCD (347, 367 and 162 aas, respectively) (Kruse et al. 2005). MreB is homologous to the chaperone protein Hsc70 (TC# 1.A.33.1.1) and the HscA homologues presented under TC#s 9.B.157.1.1 - 3. | Bacteria |
Pseudomonadota | MreBCD of E. coli |
9.B.157.1.4 | MreBCD homologues | Bacteria |
Spirochaetota | MreBCD homologues of Leptospira interrogans MreB, 409 aas (Q8F2L2) MreC, 377 aas (Q8F2L4) MreD, 170 aas (Q8F2L5) |
9.B.157.1.5 | MreBCD cell shape-determining complex: Three proteins involved in Streptomyces coeicolor spore cell wall synthesis to form the thickened septum (relative to the vegegative cell wall). MreB is 342 aas long with possibly 1 TMS at about residue 180, a second protein, MreC, which is 366 residues long with possibly 3 TMSs, one N-terminal, one at about residue 160, and one at about residue 280, and MreD, which is 223 aas long and has 5 TMSs. This system has been characterized (Sigle et al. 2015; Vollmer et al. 2019). MreB gives a TC BLAST score of e-128; MreC gives a TC BLAST score of e-10, and MreD give a TC BLAST score of 0.0001 all with 9.B.157.1.4, showing that all 3 protein constituents are homology with other members of the family, but with greatly differing degrees of sequence similarities. MreD with 5 TMSs gives a TC BLAST score of 0.0004 with T# 3.A.1.28.2, suggesting a relationship with an ABC-type membrane transport protein. | Bacteria |
Actinomycetota | MreBCD of Streptomyces coeicolor |