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9.B.17.2.4 FYVE and coiled-coil domain-containing protein 1, FYCO1, of 1478 aas and possibly two TMSs near the C-terminus of the protein. A mutation in the FYCO1 gene causes congenital cataracts (Mei et al. 2022).
Accession Number:	Q9BQS8
Protein Name:	FYVE and coiled-coil domain-containing protein 1
Length:	1478
Molecular Weight:	166983.00
Species:	Homo sapiens (Human) [9606]
Number of TMSs:	1
Location¹ / Topology² / Orientation³:	Cytoplasmic vesicle¹
Substrate

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MASTNAESQL QRIIRDLQDA VTELSKEFQE AGEPITDDST SLHKFSYKLE YLLQFDQKEK 
61:	ATLLGNKKDY WDYFCACLAK VKGANDGIRF VKSISELRTS LGKGRAFIRY SLVHQRLADT 
121:	LQQCFMNTKV TSDWYYARSP FLQPKLSSDI VGQLYELTEV QFDLASRGFD LDAAWPTFAR 
181:	RTLTTGSSAY LWKPPSRSSS MSSLVSSYLQ TQEMVSNFDL NSPLNNEALE GFDEMRLELD 
241:	QLEVREKQLR ERMQQLDREN QELRAAVSQQ GEQLQTERER GRTAAEDNVR LTCLVAELQK 
301:	QWEVTQATQN TVKELQTCLQ GLELGAAEKE EDYHTALRRL ESMLQPLAQE LEATRDSLDK 
361:	KNQHLASFPG WLAMAQQKAD TASDTKGRQE PIPSDAAQEM QELGEKLQAL ERERTKVEEV 
421:	NRQQSAQLEQ LVKELQLKED ARASLERLVK EMAPLQEELS GKGQEADQLW RRLQELLAHT 
481:	SSWEEELAEL RREKKQQQEE KELLEQEVRS LTRQLQFLET QLAQVSQHVS DLEEQKKQLI 
541:	QDKDHLSQQV GMLERLAGPP GPELPVAGEK NEALVPVNSS LQEAWGKPEE EQRGLQEAQL 
601:	DDTKVQEGSQ EEELRQANRE LEKELQNVVG RNQLLEGKLQ ALQADYQALQ QRESAIQGSL 
661:	ASLEAEQASI RHLGDQMEAS LLAVRKAKEA MKAQMAEKEA ILQSKEGECQ QLREEVEQCQ 
721:	QLAEARHREL RALESQCQQQ TQLIEVLTAE KGQQGVGPPT DNEARELAAQ LALSQAQLEV 
781:	HQGEVQRLQA QVVDLQAKMR AALDDQDKVQ SQLSMAEAVL REHKTLVQQL KEQNEALNRA 
841:	HVQELLQCSE REGALQEERA DEAQQREEEL RALQEELSQA KCSSEEAQLE HAELQEQLHR 
901:	ANTDTAELGI QVCALTVEKE RVEEALACAV QELQDAKEAA SREREGLERQ VAGLQQEKES 
961:	LQEKLKAAKA AAGSLPGLQA QLAQAEQRAQ SLQEAAHQEL NTLKFQLSAE IMDYQSRLKN 
1021:	AGEECKSLRG QLEEQGRQLQ AAEEAVEKLK ATQADMGEKL SCTSNHLAEC QAAMLRKDKE 
1081:	GAALREDLER TQKELEKATT KIQEYYNKLC QEVTNRERND QKMLADLDDL NRTKKYLEER 
1141:	LIELLRDKDA LWQKSDALEF QQKLSAEERW LGDTEANHCL DCKREFSWMV RRHHCRICGR 
1201:	IFCYYCCNNY VLSKHGGKKE RCCRACFQKL SEGPGSPDSS GSGTSQGEPS PALSPASPGP 
1261:	QATGGQGANT DYRPPDDAVF DIITDEELCQ IQESGSSLPE TPTETDSLDP NAAEQDTTST 
1321:	SLTPEDTEDM PVGQDSEICL LKSGELMIKV PLTVDEIASF GEGSRELFVR SSTYSLIPIT 
1381:	VAEAGLTISW VFSSDPKSIS FSVVFQEAED TPLDQCKVLI PTTRCNSHKE NIQGQLKVRT 
1441:	PGIYMLIFDN TFSRFVSKKV FYHLTVDRPV IYDGSDFL

9.B.17.2.4
FYVE and coiled-coil domain-containing protein 1, FYCO1, of 1478 aas and possibly two TMSs near the C-terminus of the protein. A mutation in the FYCO1 gene causes congenital cataracts (Mei et al. 2022).

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9.B.17.2.4FYVE and coiled-coil domain-containing protein 1, FYCO1, of 1478 aas and possibly two TMSs near the C-terminus of the protein. A mutation in the FYCO1 gene causes congenital cataracts (Mei et al. 2022).

Cross database links:

External Searches:

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9.B.17.2.4
FYVE and coiled-coil domain-containing protein 1, FYCO1, of 1478 aas and possibly two TMSs near the C-terminus of the protein. A mutation in the FYCO1 gene causes congenital cataracts (Mei et al. 2022).