9.B.199.1.7
Vacuolar protein sorting-associated protein 68, Vps68, of 184 aas and 4 TMSs. Vps55p and Vps68p form a complex that acts with or downstream of ESCRT
function to regulate endosomal trafficking. Loss of Vps68p disrupts
recycling to the trans-Golgi network (TGN) as well as onward trafficking to the vacuole
without preventing the formation of lumenal vesicles (Schluter et al. 2008).
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| Accession Number: | Q12016 |
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| Protein Name: | Vacuolar protein sorting-associated protein 68 |
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| Length: | 184 |
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| Molecular Weight: | 20101.00 |
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| Species: | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292] |
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| Number of TMSs: | 4 |
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| Location1 / Topology2 / Orientation3: |
Vacuole membrane1 / Multi-pass membrane protein2 |
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| Substrate |
protein polypeptide chain |
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1: MEADDHVSLF RFPFKIPTFR GIRKGGVYLS GALYALGFWI FLDAVLYSRY SNASDVHVTF
61: IDWIPFLCST LGTLIVNSIE KNRLLQGALS SDGGAFGSGV GDLDSSMAWQ ARTVLFFGFA
121: LLAGGLSGSI VVLIIKFLVK DYNTYPTLGM GVNNVLGNVC ILLSCVVLWI AQNVEDEYSY
181: SLTL