9.B.225.1.1
Estabilshed α-1,6 mannosyltransferase B, MptB of 602 aas and 11 TMSs. Involved in the initiation of core
alpha-(1,6) mannan biosynthesis of lipomannan (LM-A) and
multi-mannosylated polymer (LM-B), extending
triacylatedphosphatidyl-myo-inositol dimannoside (Ac1PIM2) and
mannosylated glycolipid,
1,2-di-O-C16/C18:1-(alpha-D-mannopyranosyl)-(1->4)-(alpha-D-glucopyranosyluronic
acid)-(1->3)-glycerol (Man1GlcAGroAc2), respectively. Catalyzes the
addition of alpha-(1->6)-mannosyl residues (Rainczuk et al. 2012).
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| Accession Number: | Q8NQ73 |
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| Protein Name: | Alpha-(1->6)-mannopyranosyltransferase B |
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| Length: | 602 |
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| Molecular Weight: | 64199.00 |
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| Species: | Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025) [196627] |
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| Number of TMSs: | 11 |
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| Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
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| Substrate |
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1: MFSAPLRRMM RVTKDEQIQP NSNAPENRKW FPRAPRPLRQ FLDTLPRIGT AGSRSATLHV
61: EDEQSPLGAT LFDVATGASS INDRDTDASG LEPEKIRRFA WLRLIGTMGA LMIAFGALGA
121: GALPVVNNPY VDFPGGNFMS RMLQTSSMIV LIGVGFLVLA WVLMAPLVGI PFKRSGNRTA
181: SVSLSMLRRT FGAWVAPIML TAPLFTQDIY SYLAQGSVTA QGMDAYAGGP LELLGPDNHL
241: ARSVPFIWAQ SPSPYGPVAL SIAASISVIT NDSIVGGVLA HRIASLLGVV AAGWAITMLA
301: RRCRVSEEAS FYLGVLNPLL ILHLIGGIHN ESILLGFLLV GLELGLRGTD RIQTGLWGPA
361: WTYIALSGVL ISCAGLVKVT GFIGLGFVGM ALARAFHARG HRHVVAIGVA GLVQVAALVI
421: TVVVLSVITG ISLGWITGQG GAATIRSWMS MTTNIGVISG FIGMNLGLGD HTAAMLVVTR
481: AAGIAVAAAF MVRMLFATYR GHIHAVGGLG VATFVLVILF PVVHPWYMLW AIVPLASWAN
541: RLFFQLGVIA YSTAFSFFVL PRGLALPVGT VFSIYFGAAL GFSILLLVGW WSLRRNPTFG
601: LH