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Accession Number: | P50076 |
Protein Name: | Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase |
Length: | 525 |
Molecular Weight: | 61793.00 |
Species: | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292] |
Number of TMSs: | 11 |
Location1 / Topology2 / Orientation3: | Endoplasmic reticulum membrane1 / Multi-pass membrane protein2 |
Substrate |
Cross database links:
Entrez Gene ID: | 853142 |
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Pfam: | PF04922 |
KEGG: | sce:YGR227W |
Gene Ontology
GO:0005789
C:endoplasmic reticulum membrane
GO:0016021
C:integral to membrane
GO:0004583
F:dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity
GO:0006488
P:dolichol-linked oligosaccharide biosynthetic process
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References (4)[1] “Isolation and characterization of genes that promote the expression of inositol transporter gene ITR1 in Saccharomyces cerevisiae.” Nikawa J.et.al. 7565092 [2] “Sequence analysis of the 43 kb CRM1-YLM9-PET54-DIE2-SMI1-PHO81-YHB4-PFK1 region from the right arm of Saccharomyces cerevisiae chromosome VII.” van der Aart Q.J.M.et.al. 8701610 [3] “The nucleotide sequence of Saccharomyces cerevisiae chromosome VII.” Tettelin H.et.al. 9169869 [4] “The ALG10 locus of Saccharomyces cerevisiae encodes the alpha-1,2 glucosyltransferase of the endoplasmic reticulum: the terminal glucose of the lipid-linked oligosaccharide is required for efficient N-linked glycosylation.” Burda P.et.al. 9597543
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External Searches:
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Analyze:
Predict TMSs (Predict number of transmembrane segments) | ||||
FASTA formatted sequence |
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1: MDAKKNTGEA NNDVLEEEAA IQLIAPGIAR NLTQEVITGI FCNVVIYPLL LIYFVLTFRY 61: MTTNIVPYEF IDEKFHVGQT LTYLKGKWTQ WDPKITTPPG IYILGLINYY CIKPIFKSWS 121: TLTILRLVNL LGGIIVFPIL VLRPIFLFNA LGFWPVSLMS FPLMTTYYYL FYTDVWSTIL 181: ILQSLSCVLT LPFGPVKSIW LSAFFAGVSC LFRQTNIIWT GFIMILAVER PAILQKQFNT 241: HTFNNYLKLF IHAIDDFSNL VLPYMINFVL FFIYLIWNRS ITLGDKSSHS AGLHIVQIFY 301: CFTFITVFSL PIWISRNFMK LYKLRIKRKP VQTFFEFIGI MLIIRYFTKV HPFLLADNRH 361: YTFYLFRRLI GNKSRLIKYF FMTPIYHFST FAYLEVMRPN QLTFHPITPL PIKEPVHLPI 421: QLTHVSWTAL ITCTMVTIVP SPLFEPRYYI LPYFFWRIFI TCSCEPLIKD LKPAKEGENP 481: ITISSTKRLF MEFLWFMLFN VVTLVIFSKV SFPWTTEPYL QRIIW