9.B.231.1.5
ALG10, the α1,2-glucosyltransferase that transfers the terminal glucose residue to the lipid-linked precursor, of 509 aas and 12 TMSs. Expressed in leaf epidermal cells with a reticular distribution pattern resembling endoplasmic reticulum (ER) localization. An insertion mutant (alg10-1)
accumulated mainly lipid-linked Glc(2) Man(9) GlcNAc(2) and displayed a
severe protein underglycosylation defect. alg10-1 mutant plants had altered leaf size when grown in soil and showed activation of the unfolded protein
response, increased salt sensitivity and suppression of the phenotype of
α-glucosidase I-deficient plants (Farid et al. 2011).
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| Accession Number: | Q8L638 |
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| Protein Name: | Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase |
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| Length: | 509 |
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| Molecular Weight: | 58439.00 |
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| Species: | Arabidopsis thaliana (Mouse-ear cress) [3702] |
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| Number of TMSs: | 12 |
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| Location1 / Topology2 / Orientation3: |
Endoplasmic reticulum membrane1 / Multi-pass membrane protein2 |
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| Substrate |
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1: MGKLAVAAIT SLWVIPMSII VNHIVPEPYM DEIFHVPQAQ QYCNGNFRSW DPMITTPPGL
61: YYLSLAHVAS LFPGMLLMEN TSQSFSEACS TSVLRSTNAV SAVLCGVLVY EIIRFLGPNL
121: SDRKATFMAL VMSLYPLHWF FTFLYYTDVA SLTAVLAMYL TCLKRRYVLS ALFGTLAVFI
181: RQTNVVWMLF VACSGILDFT LDSSKQKGKQ EVNQELHQSS NKKGATLRSN LRKRKSDISS
241: DTSDPFNHGQ TVPSTEDTSD LVYDIYTVIS TSWNLKWRIL IKFSPFIFVV VAFGIFILWN
301: GGIVLGAKEA HVVSLHFAQI MYFSLVSALF TAPLHFSVNQ LRHQFHQLHR NWSLSLILTL
361: VALVAGFVSV HFFSLAHPYL LADNRHYPFY LWRKIINAHW LMKYILVPVY VYSWFSILTL
421: LAKTRRQTWI LVYFLATCGV LVPTPLIEFR YYTIPFYLFM LHSCVRSSSF ATWLLIGTIF
481: VSINVFTMAM FLFRPFKWSH EDGVQRFIW