9.B.238.3.6
Drug sensory protein A, Dfr, Hik33, NblS, Syny4, a histidine kinase of 642 aas and 4 - 7 TMSs in a 2 + 2 or 3 + 3 + 1 TMS arrangement. It is a cell wall metabolism sensor histidine kinase, also called WalK. The transmembrane domains govern temperature responses, whereas the PAS domain may be involved in regulation of downstream gene expression in a light-dependent manner (Leusenko et al. 2023).
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| Accession Number: | AIE75112 |
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| Protein Name: | AIE75112.1 drug sensory protein A [Synechocystis sp. PCC 6714] |
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| Length: | 643 |
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| Molecular Weight: | |
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| Species: | Synechocystis sp. PCC 6714 [1147] |
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| Number of TMSs: | 3 |
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| Substrate |
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1: MWSEFNLQTR LMAAATLVVS LLMTGLTFWA VNTIQEDAQL VDTRFGRDVG LLLAANVAPM
61: IADKNLTEVA RFSSRFYENT SNIRYMIYAD PSGKIFFGIP YSEETVQNSL TLERRIELPQ
121: IDPHNFDQPF VRQHHTPNGD VTDVFIPLQY QGNSLGVLAI GINPNPAAVN SSNLTRDVTI
181: AVFISIWVMV ILGAVFNALT ITQPIKELLL GVKNIAAGNF KQRINLPFGG ELGELIVNFN
241: EMAERLERYE AQNIEELTAE KAKLDTLVST IADGAMLVDT NLQLLLVNPT ARRLFAWENK
301: PIIGENLLEN LPPEITAQLT QPLRELASDQ GSLLFGPHHQ PQEPDQDNTY APEEFRISLT
361: QPVPRTIRLM LTQVLDQTRE NLRGIVMTVQ DITREVELNE AKSQFISNVS HELRTPLFNI
421: KSFIETLSEF GEDLSEVERK EFLETANHET DRLSRLVNDV LDLSRLESSK IYQLDAVDLH
481: QLIEQSLRTY QLNAKDKQLQ LEKILDPDLP LALGNYDLLL QVMTNLIGNS LKFTKAGGKI
541: IVRAYPLHRS NLRPEEGAGL VRVEIADTGI GIDQEDQSAI FERFFRVENR VHTLEGTGLG
601: LSIVKNIIAK HQSQIHLVSE VGVGTTFWFD LAVYQSMVMV VG