9.B.334.1.3
The aerotaxis protein, Aer or YqjJ of 506 aas and 1 or 2 TMSs. The aerotactic response causes the accumulation of cells around air bubbles in liquid media under a cover slip.
The nature of the sensory stimulus detected by this protein is the
proton motive force (pmf) and the cellular redox state. It uses an FAD prosthetic
group as a redox sensor to monitor oxygen levels (Bibikov et al. 1997). The redox properties and PAS domain structure of Aer indicate a multistate sensing mechanism (Maschmann et al. 2022).
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| Accession Number: | P50466 |
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| Protein Name: | Aerotaxis receptor |
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| Length: | 506 |
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| Molecular Weight: | 55066.00 |
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| Species: | Escherichia coli (strain K12) [83333] |
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| Number of TMSs: | 1 |
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| Location1 / Topology2 / Orientation3: |
Cell inner membrane1 / Multi-pass membrane protein2 |
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| Substrate |
electron |
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1: MSSHPYVTQQ NTPLADDTTL MSTTDLQSYI THANDTFVQV SGYTLQELQG QPHNMVRHPD
61: MPKAAFADMW FTLKKGEPWS GIVKNRRKNG DHYWVRANAV PMVREGKISG YMSIRTRATD
121: EEIAAVEPLY KALNAGRTSK RIHKGLVVRK GWLGKLPSLP LRWRARGVMT LMFILLAAML
181: WFVAAPVVTY ILCALVVLLA SACFEWQIVR PIENVAHQAL KVATGERNSV EHLNRSDELG
241: LTLRAVGQLG LMCRWLINDV SSQVSSVRNG SETLAKGTDE LNEHTQQTVD NVQQTVATMN
301: QMAASVKQNS ATASAADKLS ITASNAAVQG GEAMTTVIKT MDDIADSTQR IGTITSLIND
361: IAFQTNILAL NAAVEAARAG EQGKGFAVVA GEVRHLASRS ANAANDIRKL IDASADKVQS
421: GSQQVHAAGR TMEDIVAQVK NVTQLIAQIS HSTLEQADGL SSLTRAVDEL NLITQKNAEL
481: VEESAQVSAM VKHRASRLED AVTVLH