TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
9.B.41.1.1









Occludin (with residues 70-220 comprising a MARVEL domain, and residues 430-520 comprising an Occludin_ELL domain.

Eukaryota
Metazoa
Occludin of Homo sapiens (Q16625)
9.B.41.1.2









Occludin-like protein

Eukaryota
Metazoa
Occludin-like protein of Oreochromis niloticus (Tilopia nilotica) (I3JWG5)
9.B.41.1.3









Chicken occludin.  May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Interacts with ZO-1 (Jin et al., 2008).

Eukaryota
Metazoa
Occludin of Gallus gallus (chicken)
9.B.41.1.4









Putative occludin of 483 aas.

Eukaryota
Metazoa
Occludin of Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)
9.B.41.2.1









MARVEL domain-containing protein 2, tricellulin, of 558 aas and 4 TMSs.  Plays a role in the formation of tight junctions in epithelial barriers. The separation of the endolymphatic and perilymphatic spaces of the organ of Corti from one another by epithelial barriers is required for normal hearing (Riazuddin et al. 2006).  Tricellulin forms tight junctions and is a junctional redox regulator (Cording et al. 2015).

Eukaryota
Metazoa
Tricellulin of Homo sapiens
9.B.41.2.2









Uncharacterized occludin homologue

Eukaryota
Metazoa
UP of Meleagris gallopavo (Common turkey)