9.B.447.1.1
1-acyl-sn-glycerol-3-phosphate acyltransferase, gamma, AGPAT3, of 376 aas and 2 or 3 TMSs, (One N- and either one or two C-terminal). It converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA)
into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by
incorporating an acyl moiety at the sn-2 position of the glycerol
backbone (Prasad et al. 2011).
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| Accession Number: | Q9NRZ7 |
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| Protein Name: | 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma |
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| Length: | 376 |
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| Molecular Weight: | 43381.00 |
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| Species: | Homo sapiens (Human) [9606] |
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| Number of TMSs: | 2 |
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| Location1 / Topology2 / Orientation3: |
Endoplasmic reticulum membrane1 / Multi-pass membrane protein2 |
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| Substrate |
lipopolysaccharide |
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1: MGLLAFLKTQ FVLHLLVGFV FVVSGLVINF VQLCTLALWP VSKQLYRRLN CRLAYSLWSQ
61: LVMLLEWWSC TECTLFTDQA TVERFGKEHA VIILNHNFEI DFLCGWTMCE RFGVLGSSKV
121: LAKKELLYVP LIGWTWYFLE IVFCKRKWEE DRDTVVEGLR RLSDYPEYMW FLLYCEGTRF
181: TETKHRVSME VAAAKGLPVL KYHLLPRTKG FTTAVKCLRG TVAAVYDVTL NFRGNKNPSL
241: LGILYGKKYE ADMCVRRFPL EDIPLDEKEA AQWLHKLYQE KDALQEIYNQ KGMFPGEQFK
301: PARRPWTLLN FLSWATILLS PLFSFVLGVF ASGSPLLILT FLGFVGAASF GVRRLIGVTE
361: IEKGSSYGNQ EFKKKE