1.A.102 The Influenza A viroporin PB1-F2 (PB1-F2) Family The PB1-F2 protein of 90 aas, and possibly a weakly hydrophobic C-terminal TMS, exhibits viroporin activity, transporting monovalent cations and Ca²⁺(Hyser and Estes 2015).
References:
Chanturiya, A.N., G. Basañez, U. Schubert, P. Henklein, J.W. Yewdell, and J. Zimmerberg. (2004). PB1-F2, an influenza A virus-encoded proapoptotic mitochondrial protein, creates variably sized pores in planar lipid membranes. J. Virol. 78: 6304-6312.
Hyser, J.M. and M.K. Estes. (2015). Pathophysiological Consequences of Calcium-Conducting Viroporins. Annu Rev Virol 2: 473-496.
Examples:
TC#	Name	Organismal Type	Example
1.A.102.1.1	The PB1-F2 protein of 90 aas, and possibly a weakly hydrophobic C-terminal TMS, exhibits viroporin activity, transporting monovalent cations and Ca²⁺(Hyser and Estes 2015).		PB1-F2 of Influenza virus A

1.A.102.1.2	Influenza A virus PB1-F2 protein of 57 aas		PB1-F2 of INfluenza A virus

1.A.102.1.3	PB1-F2 protein of 57 aas and 0 TMSs		PB1-F2 of Influenza A virus (A/chicken/Dongguan)

1.A.102.1.4	*PB1-F2 viroporin of 90 aas. It is an influenza A virus-encoded proapoptotic mitochondrial protein that creates variably sized pores in planar lipid membranes (Chanturiya et al.* 2004).**		PB1F2 of influenza A virus