1.A.145. The gp120 Viroporin (gp120-VP) Family This family has been examined, first, showing that its characterized member is a small transmembrane protein of 100 aas and 1 centrally located TMS (residues 45 - 69). Second, it has been shown to have ion channel activity (Basu et al. 2023). Third, its 3-D transmembrane structure has been predicted using alpha-fold.
Examples:
TC#	Name	Organismal Type	Example
1.A.145.1.1	MPXVgp120 viroporin protein of 100 aas and 1 C-terminal TMS.		MPXVgp120 viroporin of Monkeypox virus

1.A.145.1.2	Putative viroporin of 65 aas and 2 TMSs, SWPV1-219.		SWPV1-219 of Shearwater pox virus

1.A.145.1.3	IMV membrane protein, putative viroporin, of 74 aas and 1 C-terminal TMS.		Viroporin of Nile crocodilepox virus