1.B.66 The Putative Beta-Barrel Porin-2 (BBP2) Family

The BBP2 family is a large family of Gram-negative bacterial proteins with a single N-terminal TMS, probably a signal peptide, and predicted to consist of beta-barrels using the BOMP program.  These proteins are members of the DUF1597 family and are derived from several Gram-negative bacterial phyla.  Several are annotated as 'putative porin' or 'outer membrane protein'.  None seems to have been characterized.  These proteins belong to the large superfamily of beta barrel porins.



This family belongs to the Outer Membrane Pore-forming Protein I (OMPP-I) Superfamily .

 

References:

Wang, S., D. Zhao, W. Zhang, and X. Lu. (2019). Identification of a cell-surface protein involved in glucose assimilation and disruption of the crystalline region of cellulose by Cytophaga hutchinsonii. J Ind Microbiol Biotechnol 46: 1479-1490.

Examples:

TC#NameOrganismal TypeExample
1.B.66.1.1

Putative outer membrane beta-barrel porin of 447 aas.

Planctomycetes

Porin of Rhodopirellula baltica

 
1.B.66.1.2

Outer membrane protein of 404 aas.  TC BLAST give a score of e-5 with 1.B.71.1.6 and 0.003 with 1.B.1.1.15, suggesting that all three familes are members of Porin Superfamily I. This suggestion has been confirmed. The protein transports glucose and is induced by low glucose concentrations in the medium (Wang et al. 2019).

Bacteroidetes

OM Porin of Cytophaga hutchinsonii

 
1.B.66.1.3

Putative porin of 371 aas.  TC BLAST give a score of 0.002 with 1.B.12.5.2 and hits four repeats.

Proteobacteria

Porin of Thiomonas sp. 3As

 
1.B.66.1.4

Outer membrane protein of 530 aas.  TC BLAST gives a scroe of 0.004 with 1.B.16.1.3.

Spirochaetes

OMP of Leptospira sp. B5-022

 
1.B.66.1.5

Putative porin of 367 aas.

Proteobacteria

Porin of Myxococcus xanthus

 
1.B.66.1.6

Putative porin

Planctomycetes

Porin of Candidatus Kuenenia stuttgartiensis

 
1.B.66.1.7

Putative porin

Spirochaetes

Putative porin of Leptospira biflexa

 
1.B.66.1.8

Putative porin of 359 aas

Verrucomicrobia

PP of Coraliomargarita akajimensis

 
1.B.66.1.9

Putative porin of 524 aas (DUF3138 family)

Proteobacteria

PP of Burkholderia pseudomallei

 
Examples:

TC#NameOrganismal TypeExample
1.B.66.2.1

Putative porin of 413 aas

Lentisphaerae

Putative porin of Lentisphaera araneosa

 
Examples:

TC#NameOrganismal TypeExample
1.B.66.3.1

Putative porin of 474 aas

Proteobacteria

Porin of Desulfocapsa sulfexigens

 
1.B.66.3.2

Putative porin of 428 aas

Proteobacteria

Porin of Hahella chejuensis

 
1.B.66.3.3

Putative porin

Proteobacteria

PP of Oligotropha carboxidovorans

 
1.B.66.3.4

Putative porin (DUF2320 family)

Proteobacteria

PP of Agrobacterium vitis

 
Examples:

TC#NameOrganismal TypeExample
1.B.66.4.1

Putative porin of 405 aas; OMP protective antigen OMA87

Proteobacteria

OMP87 of Thioflavicoccus mobilis

 
Examples:

TC#NameOrganismal TypeExample
1.B.66.5.1

Putative porin of 511 aas; DUF2320 family.

Proteobacteria

PP of Thiobacillus denitrificans

 
Examples:

TC#NameOrganismal TypeExample