1.C.133. The Small Polypeptide Toxin (AapA1) Family This toxin family consists of toxins of 30 aas and 1 TMS that spans the membrane and forms pores. Its 3-d structure is known (PDB # 6GIG) (Nonin-Lecomte et al. 2021).
References:
Nonin-Lecomte, S., L. Fermon, B. Felden, and M.L. Pinel-Marie. (2021). Bacterial Type I Toxins: Folding and Membrane Interactions. Toxins (Basel) 13:.
Examples:
TC#	Name	Organismal Type	Example
1.C.133.1.1	*The small polypeptide toxin of 30 aas and 1 TMS. It is a type I toxin and forms pores in the membrane (Nonin-Lecomte et al.* 2021).**		AapA1 of Helicobacter pylori

1.C.133.1.2	Putative pore-forming toxin, PFT, of 30 aas and 1 C-terminal TMS.		PFT of Helicobacter pylori

1.C.133.1.3	Uncharacterized protein of 30 aas and 1 TMS		UP of Helicobacter pylori

1.C.133.1.4	Uncharacterized protein of 66 aas and 1 TMS		UP of Helicobacter pylori

Examples:
TC#	Name	Organismal Type	Example
1.C.133.2.1	Uncharacterized protein of 45 aas and 1 N-terminal TMS.		UP of Helicobacter pylori

1.C.133.2.2	Uncharacterized protein of 39 aas and 1 TMS.		UP of Helicobacter pylori

1.C.133.2.3	Uncharacterized protein of 42 aas and 1 N-terminal TMS. This protein shows appreciable seqence similarity to the protein with TC# 1.C.133.1.1 and therefore links these two subfamilies.		UP of Helicobacter pylori

1.C.133.2.4	Uncharacterized protein of 48 aas and 1 N-terminal TMS.		UP of Helicobacter pylori