1.C.141.  The Viral Pore-forming Toxin (VPT) Family 

Many viruses encode pore-forming toxins that affect animals including humans (Chong et al. 2025). Some of these are described in this family. 


 

References:

Chong, S.Y., R. Naidu, I. Othman, and S.A. Zainal Abidin. (2025). Consolidation of venom proteomes from major Cnidarian species (Scyphozoa and Cubozoa) obtained using liquid chromatography-tandem mass spectrometry. Toxicon 265: 108491.

Examples:

TC#NameOrganismal TypeExample
1.C.141.1.1

Viral pore-forming toxin of 299 aas with 1 C-terminal TMS.

Toxin of Caudoviricetes sp.

 
1.C.141.1.2

Putative toxin of 241 aas and 1 C-terminal TMS as well as 1 potential TMS ae about residue 140.

Toxin of Acetivibrio ethanolgignens

 
1.C.141.1.3

Putative partial toxin of 442 aas and 2 C-terminal TMSs.

Toxin of Enterocloster clostridioformis

 
1.C.141.1.4

Uncharacterized protein of 661 aas and 3 possible TMSs at about residues 110, 190 and 370. Each of these putative TMSs might be doublets.

UP of Lachnospiraceae bacterium