1.C.61 The Streptococcus pyogenes Streptolysin S (Streptolysin S) Family Streptolysin S of Streptococcus pyogenes is a small protein of 53 aas encoded by the pel/sagA gene. It probably contains a 17 aa leader sequence that is processed to a 36 aa polypeptide that is the key constituent of Streptolysin S. Antibodies against a C-terminal region of SagA prevents pore formation and hemolysis of sheep erythrocytes. This oxygen stable hemolysin mediates
The transport reaction catalyzed by Streptolysin S is:
small molecules (in) small molecules (out).
References:
Streptolysin S family bacteriocin of 55 aas (Molloy et al. 2011).
Streptolysin S of Streptococcus iniae
Clostridolysin BstA family, TOMM peptide of 52 aa
Clostridolysin, BstA of Clostridiaceae bacterium
Streptolysin S family bacteriocin of 50 aa
Streptolysin-like protein of Clostridium gasigenes