1.D.236.  The Chiral E-Tiling DNA NanoTube (CET-DNA-NT) Family

Structural descriptions of chiral E-tiling DNA nanotubes with the chiral indices (n,m) and handedness defined by microscopic imaging have been presented (Feng and Xiao 2023). In structural DNA nanotechnology, E-tiling DNA nanotubes are evidenced to be homogeneous in diameter, and thus have potential in biomedical applications such as cellular transport and communication, transmembrane ion/molecule channeling, and drug delivery.  Feng and Xiao 2023  summarized progress in defining the chiral indices and handedness of E-tiling DNA nanotubes by microscopic imaging, especially atomic force microscopy (AFM) imaging. Such a detailed understanding of the chiral structures of E-tiling DNA nanotubes should be helpful, on the one hand for engineering DNA nanostructures precisely, and, on the other, for realizing specific physicochemical properties and biological functions successfully.

References: