1.D.26 The Dihydrodehydrodiconiferyl alcohol 9'-O-β-D-glucoside (DDDC9G) Family

Dihydrodehydrodiconiferyl alcohol 9'-O-β-D-glucoside (DDDC9G) has antifungal activity. Choi et al. (2012) showed that DDDC9G perturbed the fungal plasma membrane and induced membrane-depolarization. The antifungal effects of DDDC9G upon the fungal plasma membrane were through the formation of pores with radii between 0.74nm and 1.4nm.

References:

Choi, H., J. Cho, Q. Jin, E.R. Woo, and D.G. Lee. (2012). Antifungal property of dihydrodehydrodiconiferyl alcohol 9'-O-β-D-glucoside and its pore-forming action in plasma membrane of Candida albicans. Biochim. Biophys. Acta. 1818: 1648-1655.